Netherville is the world in which the game takes place. It is a sleepy suburb tucked between Citytropolis and Mephistopolis. Waste has been mysteriously disposed of around town and a terrible accident spreads the toxic mess. Because of this, the landscape has been dramatically changed and it is now a apocalyptic disaster. This once-peaceful town is now inhabited by arnarchist cannibals, radioactive cults, suddenly sentient objects, and a mutant army led by the former most popular kid in school.